Emoty: an Emotionally Sensitive Conversational Agent for People with Neurodevelopmental Disorders

Our research aims at exploiting the advances in conversational technology to support people with Neurodevelopmental Disorder (NDD). NDD is a group of conditions that are characterized by severe deficits in the cognitive, emotional and motor areas and produce severe impairments in communication and social functioning. This paper presents the design, technology and exploratory evaluation of Emoty, a spoken Conversational Agent (CA) created specifically for individuals with NDD. The goal of Emoty is to help these persons enhancing communication abilities related to emotional recognition and expression, which are fundamental in any form of human relationship. The system exploits emotion detection capabilities based on the semantics of the speech by calling the IBM Watson Tone Analyzer API and from the harmonic features of the audio thanks to an “all-of-us” Deep Learning model. The design and evaluation of Emoty are based on the close collaboration among computer engineers and specialists in NDD (psychologists, neurological doctors, educators)

Axial eccentric SynRel and SPM Motors analytical models validation using 3D finite element

This paper deals with the uniform and non-uniform axial eccentricity analyses of the surface mounted permanent magnet and synchronous reluctance machines. The analyses are carried out using an analytical model for each considered machine. Being the axial eccentricity a 3D physical phenomenon, the standard sliding approach used in the analytical models has been validated through accurate 3D FE simulations. The results presented in this paper verify the effectiveness of the analytical approaches quantifying the results deviations respect to the computational expensive 3D FE simulations. The results also confirms that synchronous reluctance machines show higher radial forces compared to the surface permanent magnet machines for the same eccentricity level, main geometry and operating condition

Synchronous Reluctance Machines: A Comprehensive Review and Technology Comparison

In the last decade, the trend toward higher efficiency and higher torque density electrical machines (EMs) without permanent magnets (PMs) for the industrial sector has rapidly increased. This work discusses the latest research and industrial advancements in synchronous reluctance machines (SynRMs), being the emergent motor topology gaining wide acceptance by many industries. This article presents an extensive literature review covering the background and evolvement of SynRM, including the most recent developments. Nowadays, SynRM has found its niche in the EM market, and the reasons for that are highlighted in this work together with its advantages and disadvantages. The key journal publications in SynRM topics are discussed presenting the biggest challenges and the latest advancements with particular regards to the design methodology. This article aims to provide a thorough overview to the research community and industry about SynRM. There is a clear potential for SynRM to take over a significant portion of the EM market in the near future to meet efficiency standards in industrial applications without the use of rare-Earth PM technology

Homothetic Design in Synchronous Reluctance Machines and Effects on Torque Ripple

This paper presents a novel design concept for Synchronous Reluctance (SynRel) machines aimed at reducing the torque ripple. Two general sizing approaches based on the homothetic scaling principle are defined and compared. An in depth analysis on the torque ripple, for a wide range of scaled geometries, evaluated by finite element, has been carried out at different operating conditions. A further analysis is performed on 4 scaled geometries that have been optimized starting from 4 different rotor geometries. It is shown that the main rotor geometrical variables converge to similar values for all scaled machines. The accuracy of the proposed model is then validated by comparing the FE simulated torque ripple waveforms with the experimental data carried out, for a range of operating conditions, on a machine prototype. The outcome of this work is a fast and accurate scaling technique for the preliminary design of SynRel machines with reduced torque ripple

Independent lung ventilation in a newborn with asymmetric acute lung injury due to respiratory syncytial virus: a case report

<p>Abstract</p> <p>Introduction</p> <p>Independent lung ventilation is a form of protective ventilation strategy used in adult asymmetric acute lung injury, where the application of conventional mechanical ventilation can produce ventilator-induced lung injury and ventilation-perfusion mismatch. Only a few experiences have been published on the use of independent lung ventilation in newborn patients.</p> <p>Case presentation</p> <p>We present a case of independent lung ventilation in a 16-day-old infant of 3.5 kg body weight who had an asymmetric lung injury due to respiratory syncytial virus bronchiolitis. We used independent lung ventilation applying conventional protective pressure controlled ventilation to the less-compromised lung, with a respiratory frequency proportional to the age of the patient, and a pressure controlled high-frequency ventilation to the atelectatic lung. This was done because a single tube conventional ventilation protective strategy would have exposed the less-compromised lung to a high mean airways pressure. The target of independent lung ventilation is to provide adequate gas exchange at a safe mean airways pressure level and to expand the atelectatic lung. Independent lung ventilation was accomplished for 24 hours. Daily chest radiograph and gas exchange were used to evaluate the efficacy of independent lung ventilation. Extubation was performed after 48 hours of conventional single-tube mechanical ventilation following independent lung ventilation.</p> <p>Conclusion</p> <p>This case report demonstrates the feasibility of independent lung ventilation with two separate tubes in neonates as a treatment of an asymmetric acute lung injury.</p

Health Technology Assessment of Belimumab: A New Monoclonal Antibody for the Treatment of Systemic Lupus Erythematosus

Objective. Systemic lupus erythematosus (SLE) is treated with anti-inflammatory and immunosuppressive drugs and off-label biologics. Belimumab is the first biologic approved after 50 years as an add-on therapy for active disease. This paper summarizes a health technology assessment performed in Italy. Methods. SLE epidemiology and burden were assessed using the best published international and national evidences and efficacy and safety of belimumab were synthesized using clinical data. A cost-effectiveness analysis was performed by a lifetime microsimulation model comparing belimumab to standard of care (SoC). Organizational and ethical implications were discussed. Results. Literature review showed that SLE affects 47 per 100,000 people for a total of 28,500 patients in Italy, 50% of whom are affected by active form of the disease despite SoC. These patients, if autoantibodies and anti-dsDNA positive with low complement, are eligible for belimumab. SLE determines work disability and a 2-5-fold increase in mortality. Belimumab with SoC may prevent 4,742 flares in three years being cost-effective with an incremental costeffectiveness ratio of C32,859 per quality adjusted life year gained. From the organizational perspective, the development of clear and comprehensive clinical pathways is crucial. Conclusions. The assessment supports the use of belimumab into the SLE treatment paradigm in Italy

Standalone vertex finding in the ATLAS muon spectrometer

A dedicated reconstruction algorithm to find decay vertices in the ATLAS muon spectrometer is presented. The algorithm searches the region just upstream of or inside the muon spectrometer volume for multi-particle vertices that originate from the decay of particles with long decay paths. The performance of the algorithm is evaluated using both a sample of simulated Higgs boson events, in which the Higgs boson decays to long-lived neutral particles that in turn decay to bbar b final states, and pp collision data at √s = 7 TeV collected with the ATLAS detector at the LHC during 2011

Measurements of Higgs boson production and couplings in diboson final states with the ATLAS detector at the LHC

Measurements are presented of production properties and couplings of the recently discovered Higgs boson using the decays into boson pairs, H →γ γ, H → Z Z∗ →4l and H →W W∗ →lνlν. The results are based on the complete pp collision data sample recorded by the ATLAS experiment at the CERN Large Hadron Collider at centre-of-mass energies of √s = 7 TeV and √s = 8 TeV, corresponding to an integrated luminosity of about 25 fb−1. Evidence for Higgs boson production through vector-boson fusion is reported. Results of combined fits probing Higgs boson couplings to fermions and bosons, as well as anomalous contributions to loop-induced production and decay modes, are presented. All measurements are consistent with expectations for the Standard Model Higgs boson